Ph.D. students will be trained in he field of vaccine design including construction of vaccination antigens either wild type or chimeric based on protein, glycoprotein, or DNA/RNA; antigen modification for targeted induction of cytotoxic T cells, induction of tolerizing T cells, modification of allergen- or autoantigen-specific immune responses and induction of oral tolerance phenomenon; antigen or DNA/RNA modification for corpuscular vaccine formulation, utilizing various route of administration (systemic and mucosal) and evaluation of either systemic or mucosal immune responses in humoral and cellular arms as well as relevant intracellular signalling pathways.
Graduates in Immunopharmacotherapy will be well prepared for the coordination, design, testing and validation of preventive and therapeutic approaches and will be able to apply the results to medicine. The PhD graduate will have theoretical and practical training in laboratories focused on experimental immunology, intracellular signaling, immunopharmacology and nanotechnology.
The graduate will be educated in detail with the current possibilities of biological treatment and will be able to actively participate in the development of new biological drugs in basic and applied research. The graduate will be able to design, obtain, process and publish the results of their work in top scientific journals.
Common scientific understanding
Integrated understanding through “core” lecture courses on the basics of the field of molecular biology and immunology: Doctoral researchers of various disciplines will learn the common molecular biology knowledge that bridges their background with other disciplines and a selection of courses that emphasize skills commonly needed in immunological and farmaceutical research.
Conducting individual research through development of a thesis project. For a selection of current and past topics see our open PhD projects. https://new.imunologie.upol.cz/study-programme-immunopharmacotherapy/
Personal skills courses and strong mentoring program: Writing publications, presenting results and managing groups are key skills for internationally visible top scientists. Regular presentation of results at conferences and to external mentors will improve the training and mentoring.
Training in collaborative research through short-term research visits at foreign top research groups.This will give unique contacts to top experts in the field and increase visibility of their research projects.
Annual Fee 3 000 Euro
The length of the program is 4 years
We are not aware of any academic requirements for this programme.
We are not aware of any English requirements for this programme.
On-line application before 14th May 2021 https://www.studium.upol.cz/Catalog/StudyPrograms?type=Doctoral
Letter of motivation and research interests (in English).
Curriculum Vitae (CV) / Resume.
Documents relating to your Master's degree (or national equivalent that requires a corresponding thesis): title and abstract of your thesis, copy of your MSc certificate, copy of MSc transcript (list of courses/lectures you took, including marks).
Proof of English skills, if possible.
Any additional documents which you consider important for your application (e.g. publications, job references, certificates of workshops etc.) can be included in your CV-PDF.
Two reference letters (from e.g. former advisers) sent to us directly via email from the official work account of your chosen referees (must reach us one week after the application deadline).
Immunology - theoretical seminar
Cell signaling - theoretical seminar
Principles of pharmacology - theoretical seminar
Biotechnology - theoretical seminar
Biologicals - theoretical seminar
Modern microscopy technologies and technologies of micro and nano objects manipulations - theoretical seminar Techniques for physicochemical characterization of nanomaterials and biomolecules - theoretical seminar
Bioimaging in vivo and in vitro - theoretical seminar
Immunology - practical lessons
Cell signaling - practical lessons
Biotechnology - practical lessons
Pharmacology of nanoparticles - practical lessons
Techniques for physicochemical characterization of nanomaterials and biomolecules - practical lessons
Bioimaging in vivo and in vitro - practical lessons
Journal club Immunopharmacotherapy
Design and management of scientific research project
Medical ethics and law
Applied statistics in biomedicine
Good clinical practice
Molecular biology methods in biomedicine 1
Principles of hematological cancer diseases
Intellectual property protection
Molecular biology methods in biomedicine 2
Methods in epidemiology