Approaches for targeted drug delivery and advanced nanotherapeutics
Nanomedicine is a combination of nanotechnology and medicine. It provides new direction in medical diagnosis, monitoring and treatment at the level of single molecules or molecular assemblies at the “nano” scale. Additionally, continuing improvement in the pharmacological and therapeutic properties of drugs is driving the revolution in novel drug delivery systems.
This unique and innovating online course platform focuses mainly on the applications of nanotechnology to drug delivery and highlights several areas of opportunity where current and emerging nanotechnologies could enable novel classes of therapeutics.
The course provides an easy and effective way, the challenges and general trends in pharmaceutical nanotechnology, and also explores new strategies to overcome limitations in drug delivery. This online course teaches effectively, the recent developments in the use of nanoparticles as drug delivery systems, to treat a wide variety of diseases.
An additional benefit is that students can participate from anywhere in the world: this gives the course a global perspective and students gain valuable information about the state of nanotechnology internationally.
The course is fully supported by expert tutors who are experienced in both nanotechnology and online teaching. All of the above will be analyzed further and in detail in this online course part of the Nanotechnology - Nanomedicine category. After successfully completing the lessons, the participant will receive a training certificate.
This e-learning programme is open to suitably qualified Greek and International graduates, holding at least a Degree in Medicine Biological, Biomedical or Biochemical subject, Pharmacy, Chemistry, or in a related field.
Nanomedicine, the application of nanotechnology to medicine, has opened up a new, previously unimaginable world in disease diagnosis and therapy. Today new multifunctional nanoplatforms can be constructed that have capabilities for specific disease targeting and therapy, using moieties such as antibodies, and that contain therapeutic payloads that can be released at the disease site. The vision of combining diagnostics and therapeutics, now being referred to as theranostics, was considered futuristic only a few years ago, but is now clearly achievable – the future is almost now!
Currently, the main use of nanoparticle medicinal products (NMP) is their conjugation or/and encapsulation with several active biomolecules for therapeutic or/and diagnostic purposes, since they can be used as drug carriers for chemotherapeutics to deliver medication directly to a tumour while sparing healthy tissue.
Corresponding products already marketed, are Doxil™ (a chemotherapy drug, doxorubicin, is encapsulated in a liposome) and more recently Abraxane™ (Protein-bound paclitaxel is an injectable formulation of paclitaxel, a drug used to treat breast cancer, lung cancer, and pancreatic cancer, by preventing the normal breakdown of microtubules during cell division and thus minimizing the spread of cancer cells in the body. In this formulation, paclitaxel is bonded to albumin as a delivery vehicle).
At the same time, researchers are now focused on the construction of advanced nanotherapeutic approaches, such as DNA nanostructure carriers, nano-vaccines, and gene nano-therapy.
In this programme, critical issues of nano-based targeted drug delivery and therapy are going to be discussed. The course is also focusing on several interesting regulatory and ethical aspects of the use of nanotechnology in every day clinical practice.